Bioactive compounds in Cucumis melo L. and its beneficial health effects: a scoping review
2019
Cucumis melo L. possesses numerous medicinal and nutritive functions due to the rich sources of biological active compounds.
However, Cucumis melo L. processing generate by-products that threaten the environment. This study aims to explore the
bioactive compounds present in different melon parts and the fruit’s beneficial health effects. A methodological framework
proposed by Arksey and O’Malley was used to conduct the scoping review. An electronic database search for English
academic articles was conducted using PubMed, Scopus and ScienceDirect encompassing years between 1999 and 2019. All
types of studies, excluding systematic review or review papers were eligible for inclusion. Out of 602 studies identified, a
total of 18 studies were included. Both peels and seeds were rich in phenolic compounds. The seed oil contained rich sources
of tocopherols, while β-carotene and vitamin C were found in the flesh. Next, the main beneficial health effects included
antioxidant, anti-inflammatory, anti-ulcer, anti-angiogenic, anti-diabetic, anti-bacterial and anti-hypothyroidism activities, which
were attributable to the presence of bioactive compounds. In summary, Cucumis melo L., particularly its seeds and peels
exhibited various health benefits. This was an indicative of the potential of incorporating these by-products into various food
and nutraceutical applications to create novel functional food or dietary supplements.
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