Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial

Azzopardi et al 1 report the experience of introducing total body cooling as a standard form of therapy for infants with moderate or severe perinatal asphyxia. It is notable that this publication includes only one level 2 neonatal intensive care unit of the 25 units providing data for the TOBY register (Royal Cornwall Hospital, Truro). The Royal Devon and Exeter Hospital (also a level 2 unit) has since joined the TOBY register having participated in the TOBY trial. Part of the success in recruitment to the TOBY trial was because of the trial being rolled out to many more units in the second phase of the trial. The Peninsula Neonatal network level 3 …