Abstract 540: Angiotensin II and Reactive Oxygen Species (ROS) Induce ERK5-SUMOylation and Inhibit ERK5 Transcriptional Activity: Implication in Diabetic Cardiomyopathy (DMC)

BACKGROUND SUMOylation is a novel post translational modification system and affects on protein localization and inhibits transcriptional activities. ERK5 is a member of the MAP kinase family, whic...