A study on histology of fetal liver
2015
Background and aims : The liver during fetogenesis
does not follow classical lobular pattern. Normal histology
of the fetal liver at various stages of development was
studied to get insight into the morphology of fetal liver
and special function it performs in fetal life. Method:
Dissection of 29 normal human fetuses was done and
histological findings of liver were noted with respect to
the age of fetus. The histology of fetal liver was studied
using H & E stain and important features of fetal liver
were studied. Result: Fetal liver histology is different
from adult liver. Unlike adult liver, fetal liver shows
hepatocytes arranged in sheets predominantly with cordlike
pattern at places. The sinusoids are dilated and filled
with hemopoietic cells, which could be appreciated at
different stages of fetal development. The Kupffer cells
were also noticed in fetal liver. Conclusion: The present
study will be helpful in understanding the normal histology
of fetal liver and add to the existing knowledge regarding
development of fetal liver.
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