145 Arbovirus and related infection disease in China.

Arboviruses (arthropod-borne viruses) are maintained in nature in cycles involving hematophagous arthropod vectors such as mosquitoes, midges, ticks and susceptible vertebrate hosts human or animals. At present, more than 550 arboviruses have been identified, among which are more than 130 virus species that can cause disease in susceptible vertebrate hosts. Today, Dengue fever, West Nile virus disease, and Rift valley fever etc. still outbreak in the worldwide. Study of arboviruses not only becomes the important topics of virology, but also appears to be a social problem directly related with the public health. Japanese Encephalitis Virus (JEV), Dengue Virus (DENV), Crimean-Congo Hemorrhagic Fever Virus (CCHFV) (also known as Xinjiang Hemorrhagic Fever Virus in Chinese, XHFV), and Tick-Borne Encephalitis Virus (TBEV) are the 4 principal arboviruses of public health importance in mainland China at present. There is a growing body of evidence indicating that other arboviruses are present and causing human infections and disease in China. Over the past years, an investigation of arbovirus has been carried out in China, across the country, to learn more about arboviruses, or viruses spread by insects. The various specimens with a total number of 897, 369 have been collected from 29 provinces of mainland China, including 841, 576 mosquitoes, 16, 315 ticks, 5, 968 sandflies, 960 midges, 436 bats, 2, 309 animal specimens, 18, 579 clinical specimens from patients with fever and viral encephalitis and 13, 380 serum specimens from healthy populations. Total 512 arbovirues strains, belonging to 23 species in 10 genuses of 7 families, were isolated from various specimens, including Flavivirus, Alphavirus, Bunyavirus, dsRNA virus and DNA virus have been identified.