Immunopathology of renal disease

This reference text covers many topics concerning renal disease, such as the ways antibodies induce glomerular injury and the controls governing immune responses, giving insights into avenues for modulating and manipulating these responses for therapeutic benefit. Other subjects covered include the membrane attack complex of complements and oxidants released by inflammatory cells, the cellular immune mechanisms in glomerular and tubulointerstitial renal injury, the roles of glomerular cells as both responders and potential instigators of change, the utilization of sophisticated physiologic measurements of glomerular haemodynamics and function and the evidence for and against an immune complex aetiology for IgA nephropathy. Therapeutic techniques for the more common forms of immunologic renal injury are also examined.