Characterization of T-cell responses to cryptic epitopes in recipients of a noncodon-optimized HIV-1 vaccine.
2014
Introduction
Cryptic epitopes (CE) can be encoded by any of the 5 alternate reading frames (ARF, 2 sense and 3 antisense) of a known gene. While CE responses are commonly detected during HIV-1 infection, it is not known whether these responses are induced following vaccination.
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