Corpus callosum in developmentally retarded infants

Abstract The development of the corpus callosum was examined by magnetic resonance imaging in developmentally retarded infants ranging in age from 1–13 months. Results were compared with those of normal infants. Eighteen magnetic resonance imaging studies were performed on 18 developmentally retarded infants. Fifty-four magnetic resonance imaging studies were performed on 38 normally developed infants. The thickness of the corpus callosum was measured at a point one-third of the length of the entire corpus callosum from the most anterior aspect of the genu. The development of the corpus callosum was related to aging in both groups. There was a significant difference in the thickening of the corpus callosum between normal and developmentally retarded infants.