Efficient access to alkynylated quinalizinones via the gold(I)-catalyzed aminoalkynylation of alkynes
2016
The gold-catalyzed aminoalkynylation of alkynes for the synthesis of quinalizinones is reported. For instance, the reaction of pyridinoalkynes with 1-[(triisopropylsilyl)-ethynyl]-1,2-benziodoxol-3(1H)-one (TIPS-EBX) in the presence of a catalytic amount of AuCl at 50 °C afforded alkynylated quinalizinones in 57–87% yields.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
73
References
23
Citations
NaN
KQI