Tetrahidropiridopirimidona derivatives 3-substituted, their preparation and use.

Derivatives tetrahidropiridopirimidona 3-substituted formula I (I) wherein one of the two X radicals, Y represents CH2, and the other represents NR 1, R 1 represents hydrogen, alkyl having 1 to 6 carbon atoms ramifiado or unbranched carbon, CO-alkyl having 1 April carbon atoms, CO2tBu, CO-aryl and a phenylalkyl radical having 1 to 4 carbon atoms, which may be substituted in turn on the aromatic ring by F, Cl, Br, I, alkyl 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, trifluoromethyl, hydroxy, amino, cyano or nitro, A represents alkylene having 1 to 10 carbon atoms branched or unbranched, or alkylene of 2 to 10 carbon atoms branched or unbranched, comprising at least one group Z which is selected from O, s, NR2, cyclopropyl, CHOH, a double or a triple bond, R 2 represents hydrogen and alkyl having 1 to 4 carbon atoms, B represents 4-piperidine, 4-tetrahydro-1,2,3,6-pyridine, 4-piperazine, and the corresponding CICLI cos increased enun methylene group, where the link to A via an N atom of B, and Ar represents phenyl, which is substituted, if desired, by alkyl having 1 to 6 carbon atoms or ramicado ramicado, O- alquilocon1a 6 carbon atoms branched or unbranched, OH, F, Cl, Br, I, trifluoromethyl, NR22, CO2R2, cyano or phenyl, tetralin, indane, more highly condensed aromatic compounds such as naphthalene, which is substituted, if appropriate , alkyl having 1 to 4 atomosdecarbono uO-alquilocon1 to 4 carbon atoms, anthracene, or aromatic heterocycles of 5 or 6 members with 1 to 2 heteroatoms, which are selected independently of one another, from O and N, which may They are fused to other aromatic radicals, and salts with tolerated acids physiologically.