[Generic drugs instead of brand drugs prescriptions--long overdue].

Generic substitution of drugs was introduced in Norway in 2001. This implies an obligation for pharmacies to substitute the prescribed drug with a generic equivalent. Instead of using the drug manufacturers' trade names, doctors can prescribe drugs by using the generic (non-proprietary) names. The present paper gives an overview over current practice in different countries and discusses advantages and drawbacks.Literature on generic substitution and generic prescription was sought on PubMed. Regulatory authorities in Norway and other countries were approached for additional information.In the United Kingdom, generic prescription has been dominating for many years. In Sweden, a successful trial period with generic prescribing was recently reported. We have not identified any pharmacological arguments against generic prescription.Available data suggest that generic prescribing of drugs should be encouraged. Generic prescribing is likely to improve patient safety by assuring that the prescribed drug is in fact what is dispensed.