Evaluation of analgesic and anti-inflammatory effects of ethanol extract of Ficus iteophylla leaves in rodents.

This study was undertaken to investigate the leaf part of the plant for analgesic and anti-inflammatory. The ethanol extract of Ficus iteophylla leaves (100, 200, and 400mgkg-1, i.p) was evaluated for analgesic and anti-inflammatory activities. The analgesic effect was studied using acetic acid-induced abdominal constriction and hot plate test in mice, while the antiinflammatory effect was investigated using carrageenan induced paw oedema in rats. The ethanol extract at 100mgkg -1 , 200mgkg -1 , and 400mgkg -1 significantly (P -1 body weights. The result obtained from this study shows that the extract of Ficus iteophylla contained phytochemical constituents with analgesic and anti-inflammatory activities, therefore the leaf part of the plant could be used in the management of pain and inflammatory conditions. Key words: Ficus iteophylla , analgesic, anti-inflammatory, intraperitoneal doi: 10.4314/ajtcam.v8i4.19