Роль митохондрий в реализации механизмов программированной гибели клетки

In this review is discussed mechanisms of mitochondria participation in programmed cell death mechanisms. The mitochondria are main unit, integrating signals that activates different ways of programmed cell death: apoptosis, aytophagy, and necrosis-like programmed cell death. It is assumed that at mitochondria participate in a «choice» of cell death way. The integration of different mechanisms of cell death predetermines the possibility mitochondria use as one of main objects of cell protection from different death stimula.