Stereoselective Synthesis of Iodofluoroalkenes by Iodofluorination of Alkynes Using IF5‐Pyridine‐HF.

The iodofluorination of alkynes was carried out using IF5-pyridine-HF and hydroquinone. The iodofluorination of an internal alkyne and a terminal alkyne proceeded stereoselectively to give the corresponding iodofluoroalkenes. An unsymmetrically substituted internal alkyne and electron deficient alkyne also afforded the corresponding iodofluoroalkenes stereoselectively. The iodofluoroalkenes thus obtained were used in the stereoselective synthesis of di- and trisubstituted fluoroalkenes.