Classifying human promoters by occupancy patterns identifies recurring sequence elements, combinatorial binding, and spatial interactions
2018
Background
Characterizing recurring sequence patterns in human promoters has been a challenging undertaking even nowadays where a near-complete overview of promoters exists. However, with the more recent availability of genomic location (ChIP-seq) data, one can approach that question through the identification of characteristic patterns of transcription factor occupancy and histone modifications.
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