Anti-P-selectin

An antibody that binds to P-selectin, NoUn antibody that binds to P-selectin, does not bind complement factor Clq and tamp is fixed on the complement factor Clq nor sobrereceptores of Fcy on NK cells, oco sobrereceptores of Fcy on NK cells, containing an Fc part derived from a source h containing an Fc part derived from human origin and caracterizaporque said antibody is uumano and caracterizaporque said antibody is an antibody of human subgroup IgG4 wherein S22n antibody of human subgroup IgG4 wherein S228 is replaced by P and L235 sesustituye E, inh8 is replaced by P and L235 sesustituye E, inhibiting the adhesion of like HL60 cells to leibiendo adhesion similar HL60 cells to leukocytes to P-selectin purified a P-selectin valorIC50ucocitos purified with valorIC50 0.08 to 0.5 ug / ml and by comprising the regio 0.08 to 0.5 ug / ml and by comprising the CDR1 , CDR2 and CDR3 variable domain cadennes CDR1, CDR2 and CDR3 chain variable domain ligeradefinido by the amino acid sequence is ligeradefinido by the amino acid sequence SEQ ID NO: 3 and CDR1, CDR2 and CDR3 regions of DOQ ID NO: 3 and CDR1, CDR2 and CDR3 regions of the heavy cadenavariable domain defined by SEQminio heavy cadenavariable defined by SEQ ID NO: 4. ID NO: 4.