Glucose oxidation rates in newborn infants measured with indirect calorimetry and [U-13C]glucose.

1. Indirect calorimetry and primed constant infusion of [U- 13 C]glucose were combined in 16 appropriate-for-gestational age newborn, parenterally fed infants, in order to measure glucose utilization and glucose oxidation respectively. 2. Glucose intake ranged between 10.0 and 24.1 g day −1 kg −1 and energy intake between 156.9 and 439.3 kJ day −1 kg −1 . 3. Glucose utilization ( P P P 4. The significant difference between glucose utilization and oxidation ( P 5. As lipogenesis from glucose consumes 15-24% of the original glucose energy, the increasing metabolic rate accompanying rising glucose intake is probably due to increasing lipogenesis.