A Combined Experimental and Computational Study on the Palladium-Catalyzed Sequential [2+2+1] Spirocyclization/Arene C–H Activation of 4-Iodo-2-quinolones with Diphenylacetylene

The palladium-catalyzed reaction of 4-iodo-2-quinolones with diarylacetylenes in the presence of Ag2CO3 as a base in N,N-dimethylformamide (DMF) at 100 °C afforded unprecedented polyfused 2-quinolo...