Stabilization of HIF-1α by DMOG promotes the recovery of acute spinal cord injury by inhibiting neural apoptosis and enhancing axon regeneration

Yao Li,Wen Han,Yanqing Wu,Kailiang Zhou,Zhilong Zheng,Haoli Wang,Ling Xie,Rui Li,Ke Xu,Yanlong Liu,Xiang-Yang Wang,Jian Xiao

Stabilization of HIF-1α by DMOG promotes the recovery of acute spinal cord injury by inhibiting neural apoptosis and enhancing axon regeneration

2019

Yao Li
Wen Han
Yanqing Wu
Kailiang Zhou
Zhilong Zheng
Haoli Wang
Ling Xie
Rui Li
Ke Xu
Yanlong Liu
Xiang-Yang Wang
Jian Xiao

Abstract Spinal cord injury (SCI) is a devastating neurological disorder that usually leads to a loss of motor and sensory function in patients. The expression of hypoxia inducible factor-1α (HIF-1...

Keywords:

Anesthesia
Medicine
Cancer research
Apoptosis
Acute spinal cord injury
Axon
Spinal cord injury
Hypoxia-inducible factors
Neurological disorder
Autophagy
Hypoxia (medical)

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