Serum immunoglobulin values in children with altered spirometric values

: The authors present values of immunoglobulins IgA, IgM, IgG and IgE in 40 pupils at Sabac, who were exposed to high aeropollution and in whom spirometric pulmonary functions (vital capacity, FEV1 and FEV1/PVC relation) were under the normal or at its upper limit. Frequent respiratory diseases, sometimes followed by wheezing, were observed in these children. The aim of the study was to detect a possible predisposing factor responsible of these conditions. This was done with the control examinations of immunoglobin values when atopic constitution (IgE) or immunodeficency should be detected. IgG values were, however, within the normal. Thus, the atopic role in the onset of these respiratory disorders was excluded. High-degree aeropollution was cited as the main cause of frequent respiratory diseases and low spirometric values of the pulmonary function.