Functional relationship between retinal sensitivity threshold values assessed by standard automated perimetry in glaucoma

Abstract Objective To study the correlation between the sensitivity threshold values of the different points assessed by the Humphrey Visual Field Analyzer (24-2 Swedish interactive threshold algorithm [SITA] standard strategy) in glaucoma patients. Subjects, material and methods Prospective cross-sectorial study. One-hundred and four eyes of 104 glaucoma patients, defined by the appearance of the optic nerve head, were evaluated. Retinal threshold sensitivity points of standard automated perimetry (SA) with SITA Standard 24-2 program were obtained. The upper and the lower hemifields were studied separately. Pearson correlation coefficients were calculated between the mean threshold sensitivity value at each point of the visual hemifield and the rest of the threshold points in the same hemifield. Results Perimetric correlation maps between retinal threshold sensitivity values in the same hemifield were obtained. Most of the points showed moderate to high correlations ( r  ≥ 0.65. p Conclusions There is a functional relationship between neighboring and distant points in Humphrey Visual Field Analyzer (SITA Standard 24-2) in glaucoma patients. This correlation is related to the anatomical arrangement of ganglion cell axons. This fact enables perimetric patterns of glaucoma defects to be obtained.