Heterocyclic substituted styrene compound and application thereof
2012
The invention relates to a heterocyclic substituted styrene compound and application thereof. The invention discloses the styrene compound modified through heterocyclic radicals, alkoxy and halogen. The compound is used for testing Syk inhibition activity, results show that the compound has inhibition activity on spleen tyrosine kinase (Syk), part of the compound has strong inhibition activity on Syk, and a structural foundation is laid for further designing and developing novel Syk inhibitor rheumatoid arthritis (RA) treatment medicine.
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