A histopathological study of the effects of pulsed Nd:YAG laser irradiation on infected root canals in dogs.

The effects of pulsed Nd:YAG laser irradiation during root canal treatment of infected teeth were investigated histopathologically in dogs. One hundred and eight teeth with a single root in 15 healthy adult beagle strain dogs were used in this study. After inducing infected teeth, each root canal was shaped with up to at least a #40 K-file; then, after coating with black ink, the canal was irradiated using the following parameters: 1 W, 30 pps, for 1 and 2 s, and 2 W, 30 pps, for 2 s. The degree of inflammation of the periapical regions at 2, 4, and 8 wk was examined histopathologically by light microscopy. Inflammation of the periapical regions in the laser-treated groups was significantly less than that in the control group at 4 and 8 wk (p