Evaluation about endothelialization of drug eluting stent without no restenosis during angiographic follow up by using optical coherence tomography

Objective:To evaluate neointimal coverage after Drug Eluting Stent implantation without no restenosis during angiographic follow up by using optical coherence tomography(OCT).Methods:18 case enrolled into this project who received angiography follow up and OCT checkout.Results:1.Totally,4709 struts were analyzed and 88.6% were completely covered with neointimal,and 0.7% were partly covered and 8.1% were uncovered.The rate of late malapposition of struts was 2.6%.The average neointimal hyperplasia thickness was 0.099 mm.2.The rates of uncovered struts,late strut malapposition were different among different types of DES,and so did the average neointimal hyperplasia thickness.3.Compared with DES implantation less than 12 months,the average neointimal hyperplasia thickness increased in the group of DES implantation more than 12 months(0.1183 mm vs 0.0875 mm ;P=0.001),and uncovered struts rate were 1.7% and 6.8%respectively(P0.05),and late struts malapposition rate were 2.1% and 0.5% respectively(P0.001).Conclusion:Rate of neointimal coverage over DES at about 16-months follow-up was 90.1%,as the rate of uncoverage was 9.9%.Out study suggests that dual antiplatelet therapy might be continued16 months after DES implantation.