A comparative study of non-invasive versus invasive uradynamic assessment of bladder dysfunction in children

Objective To evaluate the value of non-invasive urodynamic study （NIUDS） in the assessment of bladder dysfunction in children. Methods A total of 155 cases of bladder dysfunction were recruited. There were 106 boys and 49 girls with an average age of 10. 46 ± 3.55 （5-18） years. Both NIUDS and invasive urodynamic Study （IUDS） were performed according to the recommendations of International Children＇s Continence Society （ICCS）. The detrusor function was graded into 3 groups of overactivity, normal and underactivity according to NIUDS. And the results from both studies were compared with Chi-square test. Results NIUDS revealed detrusor overactivity （n = 54）, normal （n = 74） and under activity （n = 27） while IUDS indicated overactivity （n = 26）, normal （n = 98） and under activity （n = 31）. Significant differences existed between two methods （P〈 0. 05）. There was statistical difference when detrusor was overactive （P〈0. 05） while no difference when detrusor was underactive （P〉0. 05）. The sensitivity, specificity and accuracy of NIUDS were 77%, 74% and 74% in detrusor overactivity, 62%, 77% and 68% in normal and 81%, 98%, 95% in underactivity respectively. Conclusions The sensitivity and specificity of NIUDS are excellent for children with detrusor underactivity. However it can not replace totally IUDS. It may be a first-choice for screening bladder dysfunction in children. Key words: Urodnamic;  Urination disorders;  Evaluaion studies