Antiretroviral therapy (ART) management of Low-Level Viremia in Taiwan (ALLEVIATE)

Introduction: This retrospective study aimed to investigate that if switch of combination antiretroviral therapy (cART) would result in viral suppression (B40 copies/mL) at 48 weeks for patients with persistent low-level viremia after having received cART for six months or more at two hospitals designated for HIV care in Taiwan. Materials and Methods: Between January 2001 and January 2013, patients were enrolled if plasma HIV RNA load (PVL) were 20 to B1000 copies/mL detected for six months or more [1,2]. Using a standardized data collection form, we recorded data of PVL and CD4 count before cART and at the detection of low-level viremia, serologies for hepatitis B and C virus, risk factors,