Cyclosporine A-enhanced cardioplegia preserves mitochondrial basal respiration after ischemic arrest.

Alexandro Hoyer,Kristin Klaeske,Jack Garnham,Philipp Kiefer,Aida Salameh,Klaus K. Witte,Michael A. Borger,Maja-Theresa Dieterlen

Cyclosporine A-enhanced cardioplegia preserves mitochondrial basal respiration after ischemic arrest.

2021

Alexandro Hoyer
Kristin Klaeske
Jack Garnham
Philipp Kiefer
Aida Salameh
Klaus K. Witte
Michael A. Borger
Maja-Theresa Dieterlen

Background:Mitochondrial permeability transition pore (mPTP) opening plays a crucial role in cell death during ischemia-reperfusion injury (IRI). Cyclosporine A (CsA) inhibits mPTP opening. This st...

Keywords:

Respiration
Medicine
Basal (phylogenetics)
MPTP
Pharmacology
Mitochondrial permeability transition pore

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