In vitro assessment of metronidazole adapted to the treatment of periodontopathies

: Chemical and biological assessment was done in vitro of a form of metronidazole for application into deep pouches in periodontal diseases. The obtained plates with metronidazole contained 1.4 mg (37%) of pure substance. Comparing the effect of metronidazole release in time against a control plate it was noted that the drug was released during 3 days in similar proportions from the chemical and biological samples.