Inhibiting fatty acid synthase in operable triple negative breast cancer.

Sagar Sardesai,Alexandra Thomas,Christopher Gallagher,Filipa Lynce,Y. Ottaviano,Tarah Jean Ballinger,Bryan P. Schneider,Anna Maria Storniolo,Amber Bauchle,Sandra K. Althouse,Susan M. Perkins,Jian-Ting Zhang,Kathy D. Miller

Inhibiting fatty acid synthase in operable triple negative breast cancer.

2020

Sagar Sardesai
Alexandra Thomas
Christopher Gallagher
Filipa Lynce
Y. Ottaviano
Tarah Jean Ballinger
Bryan P. Schneider
Anna Maria Storniolo
Amber Bauchle
Sandra K. Althouse
Susan M. Perkins
Jian-Ting Zhang
Kathy D. Miller

584Background: Fatty acid synthase (FASN) is overexpressed in 70% of newly diagnosed triple negative breast cancer (TNBC) and is associated with poor prognosis. In vitro, FASN overexpression induce...

Keywords:

Fatty acid synthase
Triple-negative breast cancer
poor prognosis
In vitro
newly diagnosed
Pathology
Cancer research
Medicine

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