Idiopathic lethal granuloma of the midline facial tissues.

Granuloma faciale (GF) is a rare chronic inflammatory dermatosis usually appearing only on the face, associated with high morbidity and mortality. Exact etiology is uncertain. We present an illustrative case of GF. A 32 year-old female patient was admitted at the infectious diseases service of the School of Medicine Buenos Aires University for presenting progressive destruction of face, nose, paranasal sinuses, palate, oral and para-oral strctures. The intra-oral examination revealed the features of GF. A biopsy at that time showed GF. GF has an unknown etiology, but possible predisposing factors include actinic exposure, radiation, trauma, allergy, or an Arthus-like reaction.