Synthesis of Novel Arylthio Derivatives of Mucochloric Acid

Stable reaction products of mucochloric acid with aromatic and heterocyclic thiols were synthesized and characterized. Under basic conditions the reactions proceeded with the substitution of the chlorine atom(s) by arylthiogroup(s), while in an acidic medium the hydroxy group at C 5 was substituted. Different types of new sulfur-containing products of di- and trisubstitution on the basis of mucochloric acid were obtained. In one case a new acyclic product—di-p-tolyl-2,3-bis-(p-tolylthio)butanedithioate—was isolated. The structure of all synthesized compounds was confirmed by IR, 1 H, and 13 C NMR spectroscopy; three compounds were characterized by single crystal X-ray diffraction.