Regarding 'moderate to severe hyperphosphataemia as an independent prognostic factor for 28-day mortality in adult patients with sepsis'.

Dear editor in chief, We have read an article written by Jang et al .1 The results of this paper and a previous study suggested that higher serum phosphate may be associated with higher mortality in individuals with sepsis.1 2 Several critical issues in the analysis should be considered in interpreting the results. The authors performed a multivariate analysis to adjust for confounders; however, blood urea nitrogen (BUN) and lactate were not included. Studies showed that blood lactate levels and BUN were positively associated with poor …