Fabrication of HA/β‐TCP scaffolds based on micro‐syringe extrusion system

2013 
Purpose – The purpose of this paper is to introduce a novel and concise technique of fabricating HA/β‐TCP composite ceramic scaffolds for bone tissue engineering via extrusion deposition method.Design/methodology/approach – A new rapid prototyping (RP) machine called motor assisted micro‐syringe (MAM) system is used in the authors' research. It is implemented to control the morphology, pore size and porosity of scaffolds precisely and to optimize their mechanical properties in this study.Findings – In the fabrication process, HA/β‐TCP ceramic composite slurry with prominent uniformity, stability and liquidity is prepared by deliberating the influential factors such as its ingredient, pH and viscosity. After optimizing the system parameters, scaffolds with homogeneous and interconnected pores in sizes ranging from 50 to 580 μm were obtained, and the whole process had excellent stability and repeatability. The average compressive strength of scaffolds with a porosity of around 50% reaches 50.33 MPa after si...
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