The cloning and sequencing of ribosomal protein S18 of parasitic protozoa, Entamoeba histolytica

A cDNA clone encoding ribosomal protein S18 has been isolated from parasitic protozoa, Entamoeba histolytica. The cDNA insert was 495 nucleotides long and an open reading frame (468 nucleotides including the stop codon) coded for 156 amino acid protein which was highly homologous with human, plant and yeast counterparts. PROSITE analysis of the ribosomal protein S1 8 in eukaryote revealed homology with prokaryotic ribosomal protein S13 signature, which is known to be involved in the initiation of translation.