Immunotropic Effects in Cultured Human Blood Mononuclear Cells Pre-exposed to Low-Level 1300 MHz Pulse-Modulated Microwave Field

The samples of mononuclear cells isolated from peripheral blood of healthy donors (N = 16) were exposed to 1300 MHz pulse‐modulated microwaves at 330 pps with 5 μs pulse width. The samples were exposed in an anechoic chamber at the average value of power density of S = 10 W/m2 (1 mW/cm2). The average specific absorption rate (SAR) was measured in rectangular waveguide and the value of SAR = 0.18 W/kg was recorded. Subsequently, the exposed and control cells were assessed in the microculture system for several parameters characterizing their proliferative and immunoregulatory properties. Although the irradiation decreased the spontaneous incorporation of 3H‐thymidine, the proliferative response of lymphocytes to phytohemagglutinin (PHA) and to Con A as well as the T‐cell suppressive activity (SAT index) and the saturation of IL‐2 receptors did not change. Nevertheless, the lymphocyte production of interleukin (IL)‐10 increased (P < .001) and the concentration of IFNγ remained unchanged or slightly decrease...