Synthesis and properties of 1-alkoxycarbonylmethy-2-alkylpyrroles

The condensation of alkyl 2,3-dichloropropyl- and alkyl 2-methoxy-3-chloropropyl ketones with aminoacetic acid alkyl ester hydrochlorides leads to 1-alkoxycarbonylmethyl-2-alkylpyrroles. The reaction of these esters with various bases gives the corresponding 1-carbonylmethyl-2-alkylpyrroles, 1-dialkyl-aminocarbonylmethyl-2-alkylpyrroles, 1-carbazoylmethyl-2-alkylpyrroles, and potassium 2-alkylpyrrolyl-1-acetate.