Anterior and posterior capsulorhexis in pediatric cataract surgery with or without trypan blue dye: Randomized prospective clinical study

Abstract Purpose To evaluate the clinical efficacy of trypan blue 0.1% dye (Blurhex®) in creating a complete anterior and posterior capsulorhexis during pediatric cataract surgery. Setting Tertiary eyecare center, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Methods In a prospective randomized study, an anterior (ACCC) and posterior (PCCC) continuous curvilinear capsulorhexis were performed in pediatric patients. In Group 1 (n = 19), the ACCC and PCCC were created without use of trypan blue dye. In Group 2 (n = 23), intracameral trypan blue dye was used to stain the anterior and posterior capsules. Results In Group 1, 14 eyes (73.6%) had a complete ACCC and 10 (52.6%) had a complete PCCC. In Group 2, 21 eyes (91.3%) had a complete ACCC and 19 (82.6%) had a complete PCCC. Conclusion In cases of pediatric cataract, staining the anterior and posterior capsules with trypan blue 0.1% allowed recognition of capsule flaps and facilitated the creation of complete ACCCs and PCCCs.