Vanadium Compounds as Insulin Mimics

V. Structures and Physical Properties 2563 A. BMOV 2563 B. VPA and VO-MPA 2564 C. VCME 2564 D. V-P 2564 E. Naglivan 2564 F. VO-SALEN 2564 G. VO(met)2 2565 VI. Biological Considerations 2565 A. Animal Models for in Vivo Testing 2565 B. Evaluation of Potency by Glucose-Lowering 2565 VII. Peroxovanadates 2566 A. [VO(O2)2(L-L′)] 2566 B. [VO(O2)2(him)] 2567 C. [VO(O2)(H2O)2(L-L′)] 2567 VIII. V(III) Complexes 2567 IX. Vanadium as a Therapeutic Agent 2568 A. Human Trials 2568 B. Desirable Features 2568 C. Potential Drawbacks 2568 X. Comparison with Other Metal-Containing Insulin Mimics 2568