One-Pot Synthesis of 2-Alkyltetrahydropyran-3-ones from 3-Nitro-5,6- dihydro-4H-pyran and Grignard Reagents.

Abstract 3-Nitro-5,6-dihydro-4H-pyran reacts with primary aliphatic and benzylic Grignard reagents and, in suitable hydrolysis conditions, gives the corresponding 2-alkyltetrahydropyran-3-ones in satisfactory yields.