Uji Aktivitas Ekstrak Etanol 70% Rimpang kencur (Kaempferia galanga L.) Terhadap Staphylococcus epidermidis

Staphylococcus epidermidis is a group of negative coagulase staphylococcus which is a normal flora and can cause infection, often associated with implantable devices such as joint prosthetics, intravascular catheters. Inappropriate or irrational use of antibiotics for unnecessary diseases and the tendency for antibiotics to be bought free or without a prescription result in the development of antibiotic-resistant bacteria. Kencur (Kaempferia galanga L) is one of the herbal plants, active substances such as alkaloids, steroids, flavonoids and saponins contained in kencur rhizome extract has antibacterial activity. To determine the antibacterial activity of 70% ethanol extract of kencur rhizome (Kaempferia galanga L.) to Staphylococcus epidermidis. This research is an experimental laboratory research that is giving treatment of 70% ethanol extract of kencur rhizome (Kaempferia galanga L.) to Staphylococcus epidermidis bacteria by post test only controlled group design method. The kencur rhizome extract was divided into several concentrations, namely 20%, 40%, 60% and 80, On the muller hilton media that had been smeared with bacteria made a 6 mm diameter well. Wells are drippedthe rhizome extract in various concentrations. Furthermore, the media was incubated for 24 hours with a temperature of 370 C then the diameter of the inhibition zone was measured by the calipers. The results of the inhibitory diameter zone outside the well of the kencur rhizome extract were concentrations of 20%, 40%, 60%, and 80%, namely 3.92 mm, 4.07 mm, 4.87 mm and 5.9 mm respectively. The Kruskal Wallis statistical test results p = 0.002. 70% ethanol extract of kencur rhizome (Kaempferia galanga L.) has antibacterial activity against Staphylococcus epidermidis. There are effects at concentrations of 20%, 40%, 60% and 80%.