Advances in research on autophagy induced by sonodynamic therapy in tumor cells

2019 
Sonodynamic therapy(SDT) has been widely concerned because of its safety, penetrability and side effects in cancer treatment. At present, it is found that there are many mechanisms for the treatment of tumors by acoustic kinetics, in which the autophagy effect of cells is gradually highlighted and recognized by people. Autophagy is an important mechanism of cell death, a widely existing physiological phenomenon newly discovered in eukaryotes, and a process in which cells self-digest. Based on the relevant literature in recent years, this paper reviews the interactions and regulatory factors between autophagy, sonodynamic therapy and tumor cells, in order to provide direction and new ideas for cancer treatment. Key words: Ultrasonic therapy; Autophagy; Neoplasms; Review
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