Hexahydro-pyrido derivatives (4,3-b) indole as antipsychotic drugs.

The invention relates to compounds of formula (I), the salts of pharmaceutically acceptable ADDITION AND OF stereochemically isomeric forms thereof, wherein Alk is C1-6alkanediyl; R1 is hydrogen, alkyl C1-6, C1-6 RILO or aryl; R2, R3 and R4 are each independently selected from hydrogen, halo, hydroxy, nitro, cyano, C1-6, C1-6 alkyloxy, trifluoromethyl, C1-6 alkylthio, mercapto, amino, MONO - AND DI (ALKYL C1-6) amino, CARBXILO, AL QUILOXICARBONILO C1-6 or C1-6 alkylcarbonyl; R5 is hydrogen, alkyl C1-6, C1-6 alkyloxy, C1-6 A LQUILTIO, or a radical of the formula - NR 8 R9, wherein R8 and R9 INDEPEND EACH ARE SELECTED FROM HIROGENO IENTEMENTE, C 1-6 alkyl, phenyl or phenylalkyl C1-6; R7 is hydrogen or alkyl C1-6; Or R6 and R7 together may form a bivalent DICAL RA FORMULA - R6-R7 -. Such compounds have antagonist activity CENTRAL dopamine and serotonin. It IS ALSO DESCRIBES preparing such compounds, compositions containing them and their use as a medicine.