Cerebellar syndrome in a man treated with natalizumab: From the National Multiple Sclerosis Society Case Conference Proceedings

A 57-year-old man with a medical history significant for bipolar disorder, depression, and anxiety presented in 2010 with bilateral lower extremity numbness progressing to perineal numbness and urinary retention. A “working” diagnosis of relapsing-remitting MS (RRMS) was supported by disseminated T2 hyperintensities on MRI investigations of the brain and spinal cord. Furthermore, CSF analysis revealed 4 unique oligoclonal bands not identified in blood. The National Multiple Sclerosis Society Case Conference Proceedings is both a live educational Webinar, in conjunction with a peer review publishing initiative from the monthly. “Diagnostic and Treatment Challenges in MS and Neuroimmunology Webinars” is sponsored by the National Multiple Sclerosis Society Fellowship Training Program and directed by Elliot M. Frohman, MD, PhD, and Teresa C. Frohman, MPAS, MSCS, PA-C, from the Dell Medical School at the University of Texas at Austin.