Reactivity study of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione toward the synthesis of bicyclic 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione analogues.
2007
A series of 10 optically pure 3,4-dihydro-1H-thieno[3,2-e]-[1,4]diazepine-2,5-dione derivatives has been synthesized in 41-75% yields on treatment of 1H-thieno [3,2-d][1,3]oxazine-2,4-dione with different natural α-amino acids.
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