Analysis of the state of lymphocyte infiltration in patients with NSCLC.

e19125 Background: Current evidence makes reference to the potential role of tumor-infiltrating lymphocytes (TILs) as a prognostic factor in many types of tumors; in non-small cell lung cancer (NSCLC) the relationship is not well determined. TILs are being studied with different methods such as immunohistochemistry and optical microscopy. The primary endpoint is to identify TILS in patients with NSCLC, classified as present or absent, and its relation to progression-free survival (PFS) and overall survival (OS). Our secondary endpoint is to establish the relationship between the TILS and treatment received. Methods: Retrospective and analytical case study of Instituto Oncologico de Cordoba, from 2004 to 2014. 166 patients with stage IIIB and IV NSCLC were analyzed. TILS are descriptively classified as present or absent. Survival curves were calculated using the Kaplan-Meier method. Results: 59% of patients had adenocarcinoma and 41% squamous cell carcinoma. 70% were men. 82% were smokers. 58% with squamou...