Investigation of Cytotoxic Effects of Inula Viscosa Extract

Inula viscosa is a type of Asteraceae family, which widely used for medicinal plant to treatment of different diseases. Inula viscosa contains many biological compounds, such as monoterpenes, sesquiterpenes, diterpenes, flavonoids. Our study aimed to investigate the cytotoxic effects of Inula viscosa extract on MCF-7 (breast carcinoma), C6 (glioblostoma cancer), MG63 (bone osteosarcoma), cancer cells and L929 (mouse fibroblostama) cell lines. Cytotoxic effects of the Inula viscosa extracts were performed by XTT assay. In this study, Inula viscosa extracts showed selective cytotoxic effect on MC-7 compared than L929 cells. The Inula viscosa extracts appear to be a promising source of new anticancer agent . Further studies are needed to identify the cytotoxic activity mechanisms on these cancer cell lines.