The Relationship Between Serum Uric Acid Levels and Clinical Features in Essential Tremor
2019
Introduction: In this study, we aimed to investigate the effect of uric acid on the disease, its severity and progression in ET patients with partially co-clinical features with Parkinson's disease (PD). Methods: Serum UA levels of 87 consecutive ET patients were measured and were matched according to age and sex with 87 healthy controls. Fahn-Tolosa-Marin scale was used for the severity of tremor. Sociodemographic characteristics, type of ET, duration of disease, and treatment modalities were evaluated. Results: The mean uric acid level was calculated as 4.986+/-2.1458 mg/dL and 6.004+/-1.523 mg/dL in the patient and control groups, respectively (p /=5 years; 6.438+/-0.286=5 years) (P=0.001). Conclusion: We hypothesize that as a result of high antioxidant properties of high serum uric acid levels, it is a biomarker that can show disease risk and progression in patients with ET as well as PD.
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