Retrospective study of the safety and effectiveness of transurethral resection of the prostate for benign prostatic hyperplasia in large prostates

Objective To discuss the safety and effectiveness of transurethral resection of the prostate (TURP) on large-size (≥80 ml) benign prostatic hyperplasia (BPH). Methods Retrospective analysis of 958 BPH patients in Southwest Hospital during January 2010 to January 2013 was conducted. The patients were grouped into ≥80 ml prostate group (Group A) and <80 ml prostate group (Group B) accor-ding to the volume of prostate. Comparison was made between the 2 groups on the safety and effectiveness of TURP. Results There were 276 patients in Group A and 682 in Group B. No significant differences were shown in average age and preoperative American society of anesthesiology score of Group A and B. Compared with Group B, decrement in hemoglobin level and blood Na+ concentration of Group A was more significant (P 0.05). At 6 months after the surgery, average maximum urinary flow rate (Qmax) increased from 5.9±2.9 ml/s to 17.1±8.2 ml/s for Group A and 6.1±3.0 ml/s to 17.5±6.4 ml/s for Group B, both groups showed significant increase in Qmax after surgery(P 0.05). Conclusion TURP is as safeand effective in treating large-size BPH as treating medium and small-size BPH. Key words: Prostatic hyperplasia; Transurethral resection of the prostate; Surgical procedures, operative