Preparation method of substituted phenyl methyl ether
2010
The present invention discloses a 2- (2,2,2-trifluoroethoxy) phenyl methyl ether preparation. In the present invention employs 2-methoxyphenol as starting material, 2,2,2-trifluoroethyl methanesulfonate substituted group substitution reaction in a basic environment. The method of preparation of the present invention, high yield, using cheap raw materials; avoid the use of chlorine atom, bromine atom, iodine atom of the leaving group, reduce pollution; process is easy to control, with a simple operation and post-processing characteristics, and safety high product quality and low cost, more suitable for industrial production.
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