Screening for IgG4-type anti-nuclear antibodies in IgG4-related disease

Kazuhiro Kiyama,Hajime Yoshifuji,Tsugumitsu Kandou,Yuji Hosono,Koji Kitagori,Ran Nakashima,Yoshitaka Imura,Naoichiro Yukawa,Koichiro Ohmura,Takao Fujii,Daisuke Kawabata,Tsuneyo Mimori

Screening for IgG4-type anti-nuclear antibodies in IgG4-related disease

2015

Kazuhiro Kiyama
Hajime Yoshifuji
Tsugumitsu Kandou
Yuji Hosono
Koji Kitagori
Ran Nakashima
Yoshitaka Imura
Naoichiro Yukawa
Koichiro Ohmura
Takao Fujii
Daisuke Kawabata
Tsuneyo Mimori

Background Immunoglobulin (Ig) G4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and infiltration of IgG4+ plasma cells into multiple organs. It is not known whether serum IgG4 is autoreactive in IgG4-RD.

Keywords:

Autoantibody
Anti-nuclear antibody
Antibody
IgG4-related disease
Biomarker (medicine)
Immunoglobulin G
Autoimmunity
Downregulation and upregulation
Immunology
Medicine
Pathology
Subclass
Antigen

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